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  8.   - Alumni
  9. Publications
  10. Notices
  11. Contact
cmoon
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MOON LAB
in Brain Sciences

Announcements

  1. Mar, 14, 2022

    2022년 콜로퀴움 일정 안내

  2. Nov, 16, 2021

    [저널클럽 및 5분토크] 2021. 11. 16.

CHEMICAL SENSES

 


Research Interests
My laboratory is studying the chemical senses of the brain.
The chemical senses have been spotlighted since Drs. Axel and Buck were awarded the Noble Prize in 2004 due to their pioneer works identifying odorant receptors and olfactory processes.
Our laboratory is studying the processes of olfaction using molecular, cellular, and morphological approaches.
Moreover, we are doing multidisciplinary translational researches for biomedical and bioengineering applications.

1. Structure and Functions of the Olfactory System
Our laboratory has tried to the cellular and molecular mechanisms underlying the olfactory signal transduction pathways.
The initial step of the olfactory pathways occurs by the interaction of odorous molecules with the odorant receptor(ORs)s in the olfactory cilia of olfactory sensory neurons(OSNs).
Investigating this detection process would be the beginning of having insights into understanding olfaction in depth.

Therefore, in our lab
1. Studying OR structure to understand the role of specific motifs of OR on its functions.
2. Studying the olfactory signaling pathway

2. Development of the Olfactory system
Our laboratory has tried to understand how neural stem cells can develop, mature, and finally integrate into the pre-existing neuronal circuit.
In the olfactory system, neuronal regeneration takes place during life. Thus the olfactory system is a good model for finding answers to this question.

Therefore, in our lab
1. Studying the developmental mechanism of the olfactory systems using rodent model systems
2. Studying the underlying cellular and molecular mechanism of development and regeneration in the olfactory systems

3. Neurodegenerative Diseases in the Olfactory System
Our laboratory has tried to understand why olfactory dysfunction appears in the early symptomatic stages of Alzheimer's disease (AD) pathology.
To date, there is no understanding of the mechanisms, implying that sensory systems may be more vulnerable to AD pathology than CNS as a whole.

Therefore, in our lab
1. Studying differences in structure and behavior in the olfactory system using AD model mice
2. Establishing the presymptomatic diagnosis of AD using human subject studies

4. Cognition in the Olfactory System
In many species, the olfactory system can play important role in survival such as reproduction and avoiding predators and foraging food.
However, compared with other sensory modalities, the olfactory system has less attention as a research topic and its cognition process has not been studied much.
In addition to structural and developmental studies, the study of the cognition process of the olfactory system can also offer important insight to understand this system.

Our laboratory has tried to understand the cognition process of odors such as odor categorization in the brain which could not be fully explained by peripheral the olfactory system.
To conduct this topic, we have used brain imaging devices such as electroencephalography(EEG) and fNIRS.

Therefore, in our lab,
1. Studying early olfactory processing in the human brain
2. Studying human odor categorization based on behavior and brain imaging studies
3. Studying human high cognition related to olfaction

Members

  - Professor

Prof. Cheil Moon

 

Prof. Cheil Moon

Dr. Moon has got his Ph.D. degree in Neurobiology at Imperial College London (UK) in 1994. Then, he joined the Department of Neuroscience, Johns Hopkins University School of Medicine in 1994, and has worked in the field of olfaction since then.
He has made many critical discoveries on olfactory signaling mechanisms and has published in many high-tier journals including Ann Reviews of Physiology, Neuron, PNAS, Journal of Neuroscience, and so on.
Since he became the very first faculty in the Department of Brain & Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Korea in 2009,
he has established a novel research field, olfactory system-related neurodegenerative disorders besides his own expertise in the olfactory signaling pathways. Recently,
he has expanded his research interests on olfactory dysfunction in Alzheimer's Disease.

Currently, he is serving as the director of Convergence Research Advanced Centre for Olfaction, DGIST.

Phone : 053-785-6110
E-mail : cmoon(at)dgist.ac.kr
Office : E4-420





  - Post-doc

배지섭(JiSub Bae)

Post-doc

배지섭(JiSub Bae)

권오훈(Oh-Hoon Kwon)

Post-doc

  - Student

심다미(Tammy Shim)

Ph. D. Candidate

심다미(Tammy Shim)

김광수(Kwangsu Kim)

Ph. D. Candidate

김광수(Kwangsu Kim)

최지윤(Choe Jiyun)

Ph. D Candidate

최지윤(Choe Jiyun)

정다혜(Da-Hae Jeong)

Ph. D. Candidate

정다혜(Da-Hae Jeong)

김원철(Won-Cheol Kim)

M.S Candidate

김원철(Won-Cheol Kim)

김도경(Do-Kyeong Kim)

M.S Candidate

김도경(Do-Kyeong Kim)

국경희(Kyung-Hee Kook)

M.S Candidate

국경희(Kyung-Hee Kook)

  - Alumni

유승준(SeungJun Yoo)

MS / PhD

유승준(SeungJun Yoo)
Max Planck Research Unit for Neurogenetics
Dr. Peter Mombaerts Lab

류상은(SangEun Ryu)

MS / PhD

류상은(SangEun Ryu)
Univ of Florida,
Dr. Daniel Wesson Lab

임승영(SeungYeong Im)

MS / PhD

임승영(SeungYeong Im)
KAIST 생명과학과

김재연(JaeYeon Kim)

MS / PhD

김재연(JaeYeon Kim)
Univ of California(San Francisco),
Dr. Parades Lab

문선애(Sunae Moon)

MS / PhD

문선애(Sunae Moon)
LG Electronics

손고운(Gowoon Son)

MS / PhD

손고운(Gowoon Son)
Univ of California (San Francisco),
Dr. Leah Goldburgh Lab

김삼환(Samhwan Kim)

PhD

김삼환(Samhwan Kim)
DGIST, Brain Engineering Convergence Research Center

이지원(Lee Jeewon)

MSc

이지원(Lee Jeewon)

이덕호(Deok ho Lee)

MSc

이덕호(Deok ho Lee)
Waseda Univ(Japan),

이주연(Juyeon Yi)

MSc

이주연(Juyeon Yi)
Wild Mobile Co.

김성환(Seonghwan Kim)

MSc

김성환(Seonghwan Kim)
DGIST Department of New Biology,
Dr. Kwak Lab

함창수(Chagnsu Ham)

MSc

함창수(Chagnsu Ham)
Private Clinic (Germany),

Rasheed Ameer

MSc

Rasheed Ameer
University of Strasbourg (France),

이선주(Lee Sun Joo)

MSc

이선주(Lee Sun Joo)

이지혜(Ji Hye Lee)

Post-doc

이지혜(Ji Hye Lee)
Univ of California(San Francisco),
Dr. Seeley Lab

박윤희(Youn Hee Park)

Post-doc

박윤희(Youn Hee Park)

김소연(SoYeon Kim)

Post-doc

DGIST, Convergence Research Advanced Centre for Olfaction

Publications

  1. Dec, 13, 2021

    Books

  2. Dec, 13, 2021

    Book Chapters

  3. Dec, 13, 2021

    Articles

Notices

  1. Jun, 24, 2022

    ECRO 2022 - Berlin

    https://www.ecro.online/meetings/ecro-2022-berlin/
  2. Nov, 16, 2021

    AChemS 2022 Call for Abstracts

    https://achems.org/2022/abstracts.php
  3. Nov, 15, 2021

    [채용] 함께할 분을 모집합니다.

Contact

(우)42988 대구광역시 달성군 현풍읍 테크노중앙대로 333
333, Techno jungang-daero, Hyeonpung-eup, Dalseong-gun, Daegu, Republic of Korea

  • [Prof. Cheil Moon]
  • Phone : +82-53-785-6110
  • E-mail : cmoon(at)dgist.ac.kr
  • [To The Lab]
  • Phone : +82-53-785-6120

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